CLOT Conversations is a podcast for healthcare professionals focused on the latest advances in thrombosis diagnosis and management. It is hosted by Dr Jameel Abdulrehman, a hematologist specializing in thrombosis and hemostasis at the University Health Network in Toronto, and David Airdrie, executive director of Thrombosis Canada. In short, digestible episodes, they discuss new research and the evolving field of thrombosis. The show is produced by Thrombosis Canada and points listeners to the organization's resources, tools, and programs for improving patient care and outcomes.
Episodes

OCEANIC-STROKE: Rethinking Secondary Stroke Prevention with Dr. Mike Sharma
Send us Fan MailFor decades, antiplatelet therapy has been central to secondary prevention following noncardioembolic ischemic stroke. Could factor XIa inhibition offer another approach?Dr. Mike Sharma, principal investigator and first author of OCEANIC-STROKE, joins Dr. Maha Othman and Dr. Jameel Abdulrehman to discuss the phase 3 trial of asundexian for secondary stroke prevention.OCEANIC-STROKE

Acute PE: New Categories, Faster Decisions and What Changes in Practice
Send us Fan MailDr. Lana Castellucci and Dr. Kerstin de Wit join CLOT Conversations to discuss the 2026 guideline for the evaluation and management of acute pulmonary embolism in adults and what its recommendations mean for clinical practice.The conversation explores the new A–E clinical categories for acute PE, including how to recognize patients whose condition may be deteriorating despite not m

EPCAT III: Is Aspirin Alone Enough After Hip or Knee Arthroplasty?
Send us Fan MailIs aspirin alone enough to prevent venous thromboembolism after total hip or knee arthroplasty?In this episode of CLOT Conversations, Dr. Jameel Abdulrehman speaks with Dr. Sudeep Shivakumar, lead author of the EPCAT III trial, recently published in the New England Journal of Medicine.EPCAT III randomized more than 5,400 patients undergoing hip or knee arthroplasty to receive aspir

Hormones, Clots, and Clinical Decisions with Dr Shannon Bates and Dr Leslie Skeith
Send us Fan MailHormone therapy is used across a wide range of clinical settings—from contraception and menopause management to pregnancy care and gender-affirming therapy. But how do these treatments influence thrombosis risk, and how should clinicians approach these decisions in practice?In this episode of CLOT Conversations, hosts Dr. Jameel Abdulrehman and Dr. Maha Othman speak with Dr. Leslie

C-TRACT Trial: Endovascular Therapy for Post-Thrombotic Syndrome with Dr. Susan Kahn
Send us Fan MailPost-thrombotic syndrome (PTS) affects up to half of patients following deep vein thrombosis and can significantly impair quality of life. Yet treatment options have historically been limited.In this episode of CLOT Conversations, David Airdrie and Dr. Jameel Abdulrehman speak with Dr. Susan Kahn about the recently published C-TRACT trial in The New England Journal of Medicine.The

Surgical and Procedural Bleed Risk Stratification in Anticoagulated Patients: ISTH Guidance in Practice
Send us Fan MailPerioperative anticoagulation management is a common and complex clinical challenge. In this episode of CLOT Conversations, Drs. James Douketis and Joseph Shaw discuss new ISTH guidance on surgical and procedural bleed risk stratification in anticoagulated patients.The discussion explores why updated guidance was needed, addressing inconsistencies in prior schemas, and introduces a

Which DOAC Bleeds Less? COBRRA Trial Insights for VTE Care with Dr Lana Castellucci
Send us Fan MailWhich DOAC bleeds less in acute VTE?In this episode, we explore the COBRRA trial comparing apixaban vs rivaroxaban and what it means for clinical practice.The COBRRA trial provides the first direct, randomized comparison of apixaban and rivaroxaban for the treatment of acute venous thromboembolism (VTE).In this episode of CLOT Conversations, Dr. Lana Castellucci discusses findings

ARTESiA: Apixaban vs Aspirin Bleeding Risk with Dr D Siegal
Send us Fan MailMajor bleeding remains the principal complication of oral anticoagulation. In patients with device-detected subclinical atrial fibrillation, the decision to anticoagulate requires careful balancing of stroke prevention against bleeding risk.In this episode of CLOT Conversations, Dr. Deborah Siegal discusses a prespecified subanalysis of the ARTESiA randomized clinical trial, recent

WAVe Study: Cancer, Obesity, Anticoagulation with Dr Tzu-Fei Wang and Dr Gregoire Le Gal
Send us Fan MailObesity presents a persistent challenge in the management of cancer-associated thrombosis, particularly when prescribing low molecular weight heparin beyond standard dose caps.In this episode of CLOT Conversations, host Dr. Jameel Abdulrehman is joined by Dr. Tzu-Fei Wang and Dr. Grégoire Le Gal to discuss findings from the WAVe study, a multicenter prospective cohort study evaluat

ROXI-VTE Trials Explained: Dr. Jeff Weitz on Next-Generation Thrombosis Prevention
Send us Fan MailIn this episode of CLOT Conversations, co-hosts Dr. Jamil Abdul-Rahman and Dr. Maha Othman have an in-depth discussion with leading thrombosis expert Dr. Jeff Weitz. Together, they unpack new findings from The Lancet on RGN-9933 and RGN-7508, two investigational factor XI inhibitors evaluated in the ROXI-VTE I and II phase-2 trials. These studies examine how targeted inhibition of

Diagnosing the “Second Clot”: Lessons from PREDICTORS with Dr Vicky Mai and Dr Grégoire Le Gal
Send us Fan MailDiagnosing recurrent venous thromboembolism (VTE) remains one of the biggest clinical challenges in thrombosis medicine. In this episode, Dr. Vicky Mai and Dr. Grégoire Le Gal join us to discuss the international PREDICTORS study (JTH, 2025), which evaluated the performance of commonly used clinical decision rules (Wells and Geneva scores) in patients with suspected recurrent VTE.

Low Health Literacy in Pediatric Thrombosis: Clinical Risks and Realities - L. Avila and J. Vincelli
Send us Fan MailThis episode reviews findings from a cross-sectional study at SickKids on health literacy in pediatric VTE patients and caregivers (Res Pract Thromb Haemost, 2025). Among 101 participants, 74% of adolescents and 59% of parents/caregivers demonstrated low general health literacy using REALM, HAS-A, and eHEALS instruments. Communication with providers was the most affected domain, an

Children and PE: Outcomes You Need to Know - L. Avila and J. Vincelli
Send us Fan MailIn this episode, Dr. Laura Avila and Jennifer Vincelli discuss their Blood publication on long-term outcomes of pediatric pulmonary embolism. Among 150 patients, ~30% had incomplete PE resolution and 9% experienced recurrence, but persistent sequelae were rare. True post-PE syndrome occurred in <9%, with only one case of CTEPH. The findings highlight the value of structured foll

Navigating Thromboprophylaxis in Orthopedic Surgery
Send us Fan MailIn this episode of CLOT Conversations, we discuss the newly developed Orthopedic Surgery VTE Thromboprophylaxis Guideline Summary. Dr. Marc Carrier, a hematologist and key author, highlights the need for a multidisciplinary approach in managing venous thromboembolism (VTE) risks, particularly in orthopedic surgery. The conversation covers preoperative risk assessments, options for

Risk Factors for Recurrent VTE in Cancer with Dr Faizan Khan
Send us Fan MailIn this episode of CLOT Conversations, experts discuss recent research on cancer-associated thrombosis and the predictors of recurrent venous thromboembolism (VTE) and anticoagulant-related bleeding. Dr. Faizan Khan, a leading researcher in the field, explains the results of their study that aimed to offer a comprehensive understanding of the prognostic factors associated with thes

Mapping Cancer's Hidden Risk—A Global Look at Blood Clots
Send us Fan MailDid you know that nearly 1 in 10 cancer patients worldwide may develop a potentially deadly blood clot? In this episode, we speak with researcher Jordan Harry, lead author of a landmark systematic review just published in Cancer Epidemiology, that uncovers which solid tumors carry the highest risk of venous thromboembolism (VTE) and where in the world patients are most vulnerable.J

INVENT VTE Dragons Den
Send us Fan MailIn this episode we speak with the three competitors from the INVENT Dragons' Den competition 2025. Hear from the researchers about their research plans that they presented in the hopes of being awarded $40,000 in funding. The researchers were: Dr Francis Couturaud (ETHER Study), Dr Leslie Skeith (PARTUM Study) and Dr Emma Leitinger (BUTTERFLY Study).Participating INVENT networ

The COBRRA Study: Shifting Paradigms in Acute VTE Treatment
Send us Fan MailIn this episode of Clot Conversations, Dr. Lana Castellucci, University of Ottawa, discusses the COBRRA study, which compares the bleeding risks of rivaroxaban and apixaban in patients with acute VTE. The study follows patients for three months and finds that apixaban significantly reduces combined bleeding events compared to rivaroxaban. While the trial wasn't powered for ind

Breakthrough in DVT Diagnosis: Age-Adjusted D-Dimer Cutoff
Send us Fan MailIn this episode of CLOT Conversations, Dr. Gregoire Le Gal, University of Ottawa, in an interview with Dr Vicky Mai, shares insights from his groundbreaking study on age-adjusted D-dimer cutoffs for diagnosing deep vein thrombosis (DVT). Previously validated for pulmonary embolism (PE), this new approach significantly improves DVT diagnostics. By adjusting D-dimer thresholds based

COPD-PE Diagnosis & Recurrent VTE with Dr Vicky Mai
Send us Fan MailIn this podcast episode, we explore groundbreaking research presented at the ISTH 2025 in Washington. Dr. Vicky May, Institut Universitaire de Cardiologie et Pneumologie de Québec, shares insights into a new diagnostic algorithm for pulmonary embolism (PE) in patients with chronic obstructive pulmonary disease (COPD). Her work focuses on identifying specific predictors, integrating

Oral anticoagulant drug considerations in Cancer: Dr Tzu-Fei Wang
Send us Fan MailIn this episode of Clot Conversations, Dr. Tzu-Fei Wang, Ottawa, shares a summary of her presentations at the 2025 ISTH meeting on recent studies on drug interactions in prostate cancer therapy and the use of anticoagulants. Dr Wang also highlights the significance of the WAVe study in assessing dalteparin use without the traditional dose cap in patients over 90 kg. These findings

Insights from Patient Experiences with VTE - Dr Stephanie Young
Send us Fan MailIn this episode of Clot Conversations, hosts Jamil Abdulrehman, and Maha Othman interview Dr Stephanie Young from Memorial University in St John's, Newfoundland, at the 2025 ISTH meeting about her presentations on the complexities of patient experiences with Venous Thromboembolism (VTE). Dr Young shares findings from a qualitative study that highlight the uncertainties and emo

Breakthroughs in Thrombosis - research insights
Send us Fan MailIn the latest episode of 'Clot Conversations,' host David Airdrie and guest Dr. Vinai Bhagirath, alongside a talented group of researchers, delve into groundbreaking thrombosis research presented at ISTH 2025. Highlights include Amulya Bhagirath's work on a computerized decision support system for anticoagulation, Dr. Alejandro Godoy's international study on LMW

Unlocking IVF Success - Dr Elvira Grandone
Send us Fan MailCLOT Conversations hosts Dr Maha Othman and Dr Jameel Abdulrehman interview Prof Elvira Grandone about two of her presentations at the 2025 ISTH conference in Washington, DC. The first is a discussion about the results of the FIRST Registry that reviews the efficacy of antithrombotic drugs in pregnancy (session OC 05.1). The second is a discussion of the Pregnancy-Associated Thromb

Reduced-Dose Apixaban for Cancer-Associated Thrombosis: A New Standard?
Send us Fan MailIn this episode of CLOT Conversations, we sit down with Dr. Marc Carrier to explore a groundbreaking study published in the New England Journal of Medicine on reduced-dose apixaban for cancer-associated venous thromboembolism (VTE). Dr. Carrier breaks down the study’s findings, which suggest that a lower dose of apixaban after six months of treatment is just as effective in prevent

Taming the Bleed: An Algorithm for Action - Deborah Siegal & Siraj Mithoowani
Send us Fan MailDrs. Mithoowani and Siegal discuss new expert guidance for managing severe bleeding in patients taking oral anticoagulants, including identifying those at risk, optimizing supportive measures, treating the source of bleeding, and administering reversal agents. It includes discussion of the algorithm for use at the point of care that helps identify patients at risk of adverse outcom

Saving Money, Saving Lives: The Impact of Anticoagulation Stewardship - Dr Tony Wan
Send us Fan MailDr Tony Wan shares the results of a study that examined the effectiveness of an anticoagulation stewardship program (ACSP) in improving adherence to venous thromboembolism (VTE) prophylaxis guidelines and reducing costs at a Canadian teaching hospital. Here what he has to say about the results and the process of setting up the study in his hospital.Tony Wan, Stephanie J. Garland, C

Canadian Stroke Best Practices - CVT
Send us Fan MailAn insightful conversation with co-authors Dr Thalia Field and Dr Jennifer Mandzia on the Canadian Stroke Best Practices 7th edition, Cerebral Vein Thrombosis. Hear from two of the guideline's authors about the latest recommendations on management of CVT.For a copy of the publication click here: Publication LinkSupport the showhttps://thrombosiscanada.caRegister today for our

ANNEXA-4 G.I. Sub-analysis - Dr Deborah Siegal
Send us Fan MailDr Deborah Siegal joins us for a discussion on the recent paper, The Efficacy and Safety of Andexanet Alfa in Patients With Acute Gastrointestinal Bleeding While Taking Factor Xa Inhibitors: An ANNEXA-4 Sub-analysis. In this wide-ranging discussion she reviews the results of the sub-analysis and the need for anticoagulant reversal for acute GI bleeding. This discussion provides her

ISTH 2023 COVID Guideline Update - Schulman & Sholzberg
Send us Fan MailThis episode of CLOT Conversations features Dr Sam Schulman (Hamilton) and Dr Michelle Sholzberg (Toronto) discussing the 2023 ISTH update of the 2022 ISTH guidelines for antithrombotic treatment in COVID-19 of which they were two of the co-authors.While COVID-19 is no longer considered a global emergency, healthcare professionals continue to see critical and non-critical cases reg

Pharmacokinetics of DOACS after Bariatric Surgery - Gunka & Mithoowani
Send us Fan MailThis podcast episode features Dr. Barbara Gunka and Dr. Siraj Mithoowani discussing their research on how bariatric surgery affects direct oral anticoagulants (DOACs).Bariatric surgery is increasingly used to fight obesity-related health problems. However, these patients often need DOACs to prevent blood clots due to surgery and obesity.The concern is that bariatric surgery might c

Spot The Clot in Cancer-associated Thrombosis - Dr Laurie Sardo & Julia Bayadinova, NP
Send us Fan MailThis podcast features an interview with Laurie Sardo and Julia Bayadinova, experts on Cancer-associated Thrombosis, from Hamilton Ontario, authors of a series of publications in the Canadian Oncology Nursing Journal on Cancer-associated Thrombosis, called Spot the Clot.Laurie Sardo is a Nurse Practitioner in the Thrombosis Service, Department of Hematology at St. Joseph's Heal

Exploring Drug-Drug Interactions in Cancer Patients - Dr Tzu-Fei Wang
Send us Fan MailIn Season 2, Episode 2 of CLOT Conversations from Thrombosis Canada, Dr. Tzu-Fei Wang, an associate professor and hematologist, discusses a recent study titled "The prevalence of relevant drug-drug interactions and associated clinical outcomes in patients with cancer-associated thrombosis on concurrent anticoagulation and anticancer or supportive care therapies." The stud

Post-thrombotic Syndrome and the TILE Study
Send us Fan MailThe CLOT Conversation Hosts (Dr Jameel Abdulrehman and Dr Maha Othman) discuss Post-Thrombotic Syndrome and the TILE study with two of the authors of the recently published paper, Tinzaparin Lead-in to Prevent the Post-Thrombotic syndrome study protocol, Dr Jean-Phillippe Galanaud and Dr Ilia Makedonov. In the interview the authors discuss the latest research on PTS and the rationa

ISTH Interview - Dr Gregoire Le Gal interviews Dr Vicky Mai
Send us Fan Mail Dr Vicky Mai presented multiple times at the ISTH 2023. Dr Le Gal talks to her about the research that she presented and the implications. The first study that she presented was a systematic review with metaanalysis on thrombolysis in intermediate high and high risk PE. The second one was an abstract on a sub analysis of the PREDICTORS study which looked at the risk of recurrent V

Interviews from the ISTH 2023
Send us Fan MailDr Abdulrehman interviews three researchers working in Canada who presented work at ISTH 2023 in Montreal. Dr Menal Huroy, reviews her poster on The Impact of GI Surgeries on peak plasma anti-Xa Direct Oral Anticoagulant levels, Dr Adam Suleman discusses his research on The Risk iof VTE in Primary CNS Lymphoma: A Systematic Review and Dr Ismail Raslan discussed his research, Antico

Statins & Post-thrombotic Syndrome - The Evidence
Send us Fan MailJoin us for an in-depth conversation with Dr Lucia Caiano and Dr Tzu-Fei Wang, two of the authors of a review exploring the potential role of statins in preventing post-thrombotic syndrome (PTS), a frequent long-term complication of deep vein thrombosis (DVT). They dive into their systematic review and meta-analysis, discussing the intriguing findings drawn from 1971 screened recor

The HIGHLOW Study with Dr Saskia Middeldorp & Dr Hanke Wiegers
Send us Fan MailIn this episode of CLOT Conversations we interview Dr Saskia Middeldorp and Dr Hanke Wiegers, authors of the groundbreaking Highlow study. This open-label, multicenter, randomized controlled trial aimed to determine the optimal dose of low-molecular-weight heparin (LMWH) for pregnant and postpartum women with a history of venous thromboembolism (VTE). Discover the study's find

Thrombotic & Bleeding Outcomes following AC interruption in NVAF and Ca with Dr Joseph Shaw & Dr Tzu-Fei Wang
Send us Fan MailDon't miss our latest podcast interview with Dr Joseph Shaw and Dr Tzu-Fei Wang who discuss insights from their single-center retrospective cohort study, which included 264 patients with nonvalvular AF and Cancer undergoing 302 periprocedural interruptions. Learn about the primary endpoints, which were the 30-day risks of arterial thromboembolism and major bleeding, and the re

DOACs vs VKAs in thrombotic APS - Dr Jean Connors & Dr Behnood Bikdeli
Send us Fan MailIn this interview, two of the authors of the paper Direct oral anticoagulants vs vitamin-K antagonists in thrombotic antiphospholipid syndrome: meta-analysis of randomized controlled trials, Dr Jean Connors and Dr Benhood Bikdeli, provide listeners with an overview of their systematic review and meta-analysis that evaluated the efficacy and safety of direct oral anticoagulants (DOA

Antithrombotic Stewardship with Dr Maral Koolian & Ryan Kerzner
Send us Fan MailAre you curious about how to improve the safety and effectiveness of anticoagulant prescriptions for hospitalized patients? Join us for an exclusive interview with two of the authors (Dr Maral Koolian and Pharmacist Ryan Kerzner ) of a groundbreaking study on anticoagulation stewardship program at the Montreal Jewish General Hospital. Our guests will share their findings on the suc

Diagnosis & Mgmt of SCPCD with Dr M Othman & Dr L Brandao
Send us Fan MailIn this episode we interview two of the authors of a recent paper, Diagnosis and management of severe congenital protein C deficiency (SCPCD): Communication from the SSC of the ISTH, Dr Maha Othman and Dr Leonardo Brandao on this paper from the Journal of Thrombosis and Haemostasis. 2022;20:1735–1743. Severe congenital protein C deficiency (SCPCD) is rare and there is currently sub

Br J Haem VTE & COC Review and Meta-analysis Abdulrehman & Skeith
Send us Fan MailTwo of the co-authors (Dr Jameel Abdulrehman and Dr Leslie Skeith) of the recently published review and meta-analysis, "Recurrence after stopping anticoagulants in women with combined oral contraceptive-associated venous thromboembolism: A systematic review and meta-analysis" (https://doi.org/10.1111/bjh.18331) discuss the clinical relevance of the results and implication

2022 CHEST Perioperative Guidelines with Dr J Douketis
Send us Fan MailIn this episode we will be discussing a recent paper published in CHEST entitled Perioperative Management of Antithrombotic Therapy: An American College of Chest Physicians Clinical Practice Guideline with lead author Dr Jim Douketis. Dr. Douketis is Staff Physician in General Internal Medicine and Clinical Thromboembolism at St. Joseph’s Healthcare Hamilton. He is a Professor of M

mRNA COVID Vaccines & VTE with M Nicholson and N Chan
Send us Fan MailIn this episode have a conversation with Dr Matthew Nicholson and Dr Noel Chan on their recent publication from Blood Review entitled No apparent association between mRNA COVID-19 vaccination and venous thromboembolism (https://www.sciencedirect.com/science/article/pii/S0268960X22000443) which was co-authored by Dr Hadi Goubran and Dr Deborah Siegal.Dr. Matthew Nicholson is a Clini

ISTH 2022 Day 4 Highlights with Thrombosis Canada
Send us Fan MailThis episode recorded at the ISTH2022 meeting in London features interviews with Dr Rita Selby and Dr James Douketis with Dr Jameel Abdulrehman. Support the showhttps://thrombosiscanada.caRegister today for our upcoming conference on November 7, 2026 in Montreal at https://thrombosiscanada.ca/2026ConferenceTake a look at our healthcare professional and patient resources, videos and

ISTH 2022 Day 3 Highlights with Thrombosis Canada
Send us Fan MailThrombosis Canada members Mark Crowther and Taylor Drury join host Jameel Abdulrehman in a discussion on some highlights from the 2022 ISTH meeting in London. Support the showhttps://thrombosiscanada.caRegister today for our upcoming conference on November 7, 2026 in Montreal at https://thrombosiscanada.ca/2026ConferenceTake a look at our healthcare professional and patient resourc

ISTH 2022 Day 2 Highlights with Thrombosis Canada
Send us Fan MailThrombosis Canada members Jameel Abdulrehman, Tsu-Fei Wang, Marc Carrier, Joseph Shaw and Yan Xu discuss their highlights from day 2 of the ISTH 2022 program. Support the showhttps://thrombosiscanada.caRegister today for our upcoming conference on November 7, 2026 in Montreal at https://thrombosiscanada.ca/2026ConferenceTake a look at our healthcare professional and patient resourc

ISTH2022 Day 1 with Jameel Abdulrehman and Maha Othman
Send us Fan MailThe 2022 International Society on Thrombosis and Haemostasis (ISTH) annual meeting is the first fully in-person meeting since the start of the pandemic in 2020. A number of Thrombosis Canada members are attending sessions throughout the program and we have invited those who can, to share their insights from the sessions that they think are key with our podcast audience. These short

CCS 2022 PAD Guidelines with Dr Sonia Anand and Dr Eric Kaplovitch
Send us Fan MailIn this episode we discuss a recent paper published in The Canadian Journal of Cardiology entitled Canadian Cardiovascular Society 2022 Guidelines for Peripheral Arterial Disease and co-authored by a national team of Canadian expertsWe are joined today by the two of the authors, Dr Sonia Anand and Dr. Eric KaplovitchDr. Sonia Anand is Professor of Medicine and Epidemiology, and a V

New GI Guidelines on Management of GI Bleeds with Alan Barkun & Jim Douketis
Send us Fan MailIn this episode we discuss a recent paper published jointly in The American Journal of Gastroenterology and the Journal of the Canadian Association of Gastroenterology entitled American College of Gastroenterology-Canadian Association of Gastroenterology Clinical Practice Guideline: Management of Anticoagulants and Antiplatelets During Acute Gastrointestinal Bleeding and the Perien

The RAPID Trial - a discussion with Dr Michelle Sholzberg
Send us Fan MailIn this episode have a conversation with Dr Michelle Sholzberg on her recent publication from the British Medical Journal entitled Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial (BMJ 2021; 375 doi: https:

Risk of VTE Recurrence with Subsegmental PE not anticoagulated
Send us Fan MailWelcome to Episode 6 of CLOT Conversations from Thrombosis Canada. In this episode Dr Jameel Abdulrehman and David Airdrie are joined by Dr Gregoire Le Gal and Dr Marc Carrier, two of the authors of a recently published paper on the entitled Risk for Recurrent Venous Thromboembolism in Patients With Subsegmental Pulmonary Embolism Managed Without Anticoagulation. The paper was publ

POISE-3 Tranexamic Acid in Noncardiac Surgery
Send us Fan MailWelcome to Episode 5 of CLOT Conversations from Thrombosis Canada. In this episode Dr Jameel Abdulrehman and David Airdrie are joined by Dr PJ Devereaux and Dr M Marcucci, two of the authors of a recently published paper on the POISE-3 study entitled Tranexamic Acid in Patients Undergoing Noncardiac Surgery. The paper was published in the New England Journal of Medicine (New Englan

Anti-seizure & Anticoagulant medications & interactions
Send us Fan MailThis is Episode 4 of CLOT Conversations from Thrombosis Canada. In this episode Dr Jameel Abdulrehman and David Airdrie are joined by Dr Vinai Bhagirath and Dr Sam Schulman, two of the authors of a recently published paper entitled Carbamazepine, phenytoin, and oral anticoagulants: Drug-drug interaction and clinical events in a retrospective cohort. The paper was published in Resea

Evaluation of definitions of OAC-associated major bleeding
Send us Fan MailIn this episode Dr Jameel Abdulrehman and David Airdrie are joined by Dr Yan Xu, one of the authors of a recently published review paper entitled Evaluation of definitions for oral anticoagulant-associated major bleeding: A population-based cohort study, co-authored by Yan Xu, Tara Gomes, Philip S. Wells, Priscila Pequeno, Ana Johnson, and Michelle Sholzberg. The paper was publishe

Canadian Cancer-associated Thrombosis Algorithm Update 2021
Send us Fan MailIn this episode we are joined by Dr Vicky Tagalakis and Dr Marc Carrier, two of the authors of a recently published review paper entitled Treatment Algorithm in Cancer-Associated Thrombosis: Updated Canadian Expert Consensus. The paper was published in Current Oncology (Curr. Oncol. 2021, 28, 5434–5451. https://www.mdpi.com/1718-7729/28/6/453). The authors speak about why this upda

Episode 1: Interview with Dr Sameer Parpia and Dr Kerstin De Wit
Send us Fan MailWelcome to Episode 1 of CLOT Conversations from Thrombosis Canada. In this episode Dr Jameel Abdulrehman and David Airdrie are joined by Dr Sameer Parpia and Dr Kerstin De Wit, two of the authors of a recently published paper entitled Diagnosis of deep vein thrombosis with D-dimer adjusted to clinical probability: prospective diagnostic management study. The paper was published in

CLOT Conversations Intro
Send us Fan MailAn introduction to CLOT Conversations a new podcast for healthcare professionals with interviews and discussions on advances in thrombosis management. Support the showhttps://thrombosiscanada.caRegister today for our upcoming conference on November 7, 2026 in Montreal at https://thrombosiscanada.ca/2026ConferenceTake a look at our healthcare professional and patient resources, vide











